TRAF3IP1 抗体
Quick Overview for TRAF3IP1 抗体 (ABIN7119988)
抗原
See all TRAF3IP1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TRAF3IP1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- TNF receptor-associated factor 3 interacting protein 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TRAF3IP1 (TNF Receptor-Associated Factor 3 Interacting Protein 1 (TRAF3IP1))
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别名
- TRAF3IP1
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背景
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Synonyms: TRAF3-interacting protein 1|Interleukin-13 receptor alpha 1-binding protein 1|Intraflagellar transport protein 54 homolog|Microtubule-interacting protein associated with TRAF3 (MIP-T3)|TRAF3IP1|IFT54|MIPT3
Background: Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Involved in kidney development and epithelial morphogenesis. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels(PubMed:26487268). Involved in ciliogenesis(By similarity).
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分子量
- 83 kDa
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基因ID
- 26146
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UniProt
- Q8TDR0
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途径
- Hedgehog Signaling
抗原
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