SYNGAP1 抗体
Quick Overview for SYNGAP1 抗体 (ABIN7119648)
抗原
See all SYNGAP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- SYNGAP1 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- synaptic Ras GTPase activating protein 1 homolog(rat)
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:2000, IF: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))
-
别名
- SYNGAP1
-
背景
-
Synonyms: Ras/Rap GTPase-activating protein SynGAP|Neuronal RasGAP|Synaptic Ras GTPase-activating protein 1 (Synaptic Ras-GAP 1)|SYNGAP1|KIAA1938
Background: Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits(By similarity).
-
分子量
- 148 kDa
-
基因ID
- 8831
-
UniProt
- Q96PV0
-
途径
- Regulation of long-term Neuronal Synaptic Plasticity
抗原
-