SOCS6 抗体
Quick Overview for SOCS6 抗体 (ABIN7119606)
抗原
See all SOCS6 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SOCS6 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- suppressor of cytokine signaling 6
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))
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别名
- SOCS6
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背景
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Synonyms: Suppressor of cytokine signaling 6 (SOCS-6)|Cytokine-inducible SH2 protein 4 (CIS-4)|Suppressor of cytokine signaling 4 (SOCS-4)|SOCS6|CIS4|SOCS4
Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS(Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins(By similarity). Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor.
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分子量
- 70 kDa
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基因ID
- 9306
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UniProt
- O14544
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途径
- JAK/STAT Signaling, Carbohydrate Homeostasis
抗原
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