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SENP3 抗体

This anti-SENP3 antibody is a 兔 多克隆 antibody detecting SENP3 in WB, ELISA 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7119591
发货至: 中国

Quick Overview for SENP3 抗体 (ABIN7119591)

抗原

See all SENP3 抗体
SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))

适用

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  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 32
  • 1

克隆类型

  • 33
多克隆

标记

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  • 2
  • 1
  • 1
  • 1
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  • 1
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This SENP3 antibody is un-conjugated

应用范围

  • 24
  • 14
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  • 5
  • 3
  • 2
  • 2
  • 1
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  • 1
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Western Blotting (WB), ELISA, Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    SUMO1/sentrin/SMT3 specific peptidase 3

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:200-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))

    别名

    SENP3

    背景

    Synonyms:SSP3, SUSP3 Background:Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regulation of sumoylation status of ZNF148. Functions as a component of the Five Friends of Methylated CHTOP(5FMC) complex, the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.

    分子量

    65-70 kDa

    基因ID

    26168

    UniProt

    Q9H4L4
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