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STIM1 抗体

This anti-STIM1 antibody is a 兔 多克隆 antibody detecting STIM1 in WB, IHC, ELISA, IP, IF 和 FACS. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7119554
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for STIM1 抗体 (ABIN7119554)

抗原

See all STIM1 抗体
STIM1 (Stromal Interaction Molecule 1 (STIM1))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This STIM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 原理

    STIM1 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    stromal interaction molecule 1

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:1000, IP: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    STIM1 (Stromal Interaction Molecule 1 (STIM1))

    别名

    STIM1

    背景

    Synonyms: Stromal interaction molecule 1|STIM1|GOK

    Background: STIM1, also named as GOK, is an ER Ca2+ sensor. Upon Ca2+ store depletion, STIM1 clusters at ER-plasma membrane junctions where it interacts with and gates Ca2+-permeable Orai1 ion channels. STIM1 is implicated in tumor growth suppression and stromal-haematopoietic cell interactions. Defacts in STIM1 gene can cause immune dysfunction with impaired T-cell activation. STIM1 can inhibit L-type voltage-gated Ca(2+) channels in neurons. Temperature is an important regulator of STIM1 function.The MW of STIM1 is about 80-90 kDa which may be due to the phosphorylation or glycosylation forms. This antibody is rabbit polyclonal antibody raised against the N-terminal of human STIM1.

    分子量

    80 kDa

    基因ID

    6786

    UniProt

    Q13586

    途径

    TCR Signaling, BCR Signaling
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