STIM1 抗体
Quick Overview for STIM1 抗体 (ABIN7119553)
抗原
See all STIM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- STIM1 antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- stromal interaction molecule 1
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亚型
- IgG2a
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应用备注
- WB: 1:200-1:2000 IHC: 1:50-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- STIM1 (Stromal Interaction Molecule 1 (STIM1))
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别名
- STIM1
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背景
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Synonyms: Stromal interaction molecule 1|STIM1|GOK
Background: Plays a role in mediating store-operated Ca(2+) entry(SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores(By similarity). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+)(CRAC) channel subunit ORAI1(PubMed:16208375). Involved in enamel formation(By similarity). Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch(By similarity).
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分子量
- 77 kDa
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基因ID
- 6786
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UniProt
- Q13586
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途径
- TCR Signaling, BCR Signaling
抗原
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