STOML2 抗体
Quick Overview for STOML2 抗体 (ABIN7119538)
抗原
See all STOML2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- STOML2 antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- stomatin(EPB72)-like 2
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亚型
- IgG2a
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应用备注
- WB: 1:2000-1:10000, IP: 1:500-1:1000, IHC: 1:50-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- STOML2 (Stomatin (EPB72)-Like 2 (STOML2))
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别名
- STOML2
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背景
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Synonyms: Stomatin-like protein 2, mitochondrial (SLP-2)|EPB72-like protein 2|Paraprotein target 7 (Paratarg-7)|STOML2|SLP2
Background: Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.
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分子量
- 39 kDa
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基因ID
- 30968
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UniProt
- Q9UJZ1
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途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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