SPO11 抗体
Quick Overview for SPO11 抗体 (ABIN7119445)
抗原
See all SPO11 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SPO11 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- SPO11 meiotic protein covalently bound to DSB homolog
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SPO11 (SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))
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别名
- SPO11
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背景
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Synonyms: Meiotic recombination protein SPO11|Cancer/testis antigen 35 (CT35)|SPO11
Background: Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks(DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2.
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分子量
- 55-70 kDa
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基因ID
- 23626
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UniProt
- Q9Y5K1
抗原
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