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Sphingomyelin Synthase 1 抗体

SGMS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7119418
发货至: 中国
  • 抗原 See all Sphingomyelin Synthase 1 (SGMS1) 抗体
    Sphingomyelin Synthase 1 (SGMS1)
    适用
    • 27
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    • 1
    人, 小鼠, 大鼠
    宿主
    • 42
    克隆类型
    • 42
    多克隆
    标记
    • 14
    • 5
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    • 1
    • 1
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    This Sphingomyelin Synthase 1 antibody is un-conjugated
    应用范围
    • 38
    • 19
    • 14
    • 13
    • 13
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    sphingomyelin synthase 1
    亚型
    IgG
    Top Product
    Discover our top product SGMS1 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    Sphingomyelin Synthase 1 (SGMS1)
    别名
    SGMS1 (SGMS1 产品)
    别名
    MGC81436 antibody, TMEM23 antibody, MOB antibody, MOB1 antibody, SMS1 antibody, hmob33 antibody, 9530058O11Rik antibody, AI841905 antibody, C80702 antibody, Mob antibody, Sms1 antibody, Sor1 antibody, Tmem23 antibody, sphingomyelin synthase 1 antibody, sphingomyelin synthase 1 S homeolog antibody, phosphatidylcholine:ceramide cholinephosphotransferase 1 antibody, SGMS1 antibody, sgms1.S antibody, LOC100013212 antibody, Sgms1 antibody
    背景
    Synonyms:MOB, SMS1, TMEM23 Background:Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
    分子量
    50 kDa
    基因ID
    259230
    UniProt
    Q86VZ5
    途径
    Cellular Response to Molecule of Bacterial Origin
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