SNX27 抗体
This anti-SNX27 antibody is a 兔 多克隆 antibody detecting SNX27 in ELISA, WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for SNX27 抗体 (ABIN7119360)
抗原
See all SNX27 抗体
SNX27
(Sorting Nexin 27 (SNX27))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This SNX27 antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- sorting nexin family member 27
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亚型
- IgG
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anti-Sorting Nexin 27 (SNX27) (AA 458-497) antibody
SNX27 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 27 (SNX27) (C-Term) antibodySNX27 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- SNX27 (Sorting Nexin 27 (SNX27))
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别名
- SNX27
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背景
- Synonyms:KIAA0488 Background:Involved in the retrograde transport from endosome to plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. Following internalization, endocytosed transmembrane proteins are delivered to early endosomes and recycled to the plasma membrane instead of being degraded in lysosomes. SNX27 specifically binds and directs sorting of a subset of transmembrane proteins containing a PDZ-binding motif at the C-terminus: following interaction with target transmembrane proteins, associates with the retromer complex, preventing entry into the lysosomal pathway, and promotes retromer-tubule based plasma membrane recycling. SNX27 also binds with the WASH complex. Interacts with membranes containing phosphatidylinositol-3-phosphate(PtdIns(3P)). May participate in establishment of natural killer cell polarity. Recruits CYTIP to early endosomes.
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分子量
- 52-60 kDa
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基因ID
- 81609
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UniProt
- Q96L92
抗原
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