SNAIL 抗体
Quick Overview for SNAIL 抗体 (ABIN7119198)
抗原
See all SNAIL (SNAI1) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- snail homolog 1(Drosophila)
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亚型
- IgG
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anti-SNAIL (SNAI1) (AA 1-100) antibody
SNAI1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) (C-Term) antibodySNAI1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) (C-Term) antibodySNAI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) (N-Term) antibodySNAI1 适用: 人, 小鼠, 大鼠, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) (AA 121-230) antibodySNAI1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2G11 unconjugated
anti-SNAIL (SNAI1) (AA 1-264) antibodySNAI1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) (AA 9-39), (N-Term) antibodySNAI1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01400 unconjugated
anti-SNAIL (SNAI1) antibodySNAI1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) antibodySNAI1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) antibodySNAI1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:5000, IHC: 1:50-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- SNAIL (SNAI1)
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别名
- SNAI1
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背景
- Synonyms:Protein sna, Protein snail homolog 1, SLUGH2, SNA, SNAH, SNAI1, snail homolog 1(Drosophila), SNAIL1, Zinc finger protein SNAI1 Background:Involved in induction of the epithelial to mesenchymal transition(EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate(TPA)-induced up-regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself.
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分子量
- 29KD
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基因ID
- 6615
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UniProt
- O95863
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途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
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