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SMN1 抗体

This 小鼠 单克隆 antibody specifically detects SMN1 in WB, ELISA 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7119175
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SMN1 抗体 (ABIN7119175)

抗原

See all SMN1 抗体
SMN1 (Survival of Motor Neuron 1, Telomeric (SMN1))

适用

  • 112
  • 50
  • 47
  • 6
  • 6
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 86
  • 26
小鼠

克隆类型

  • 66
  • 46
单克隆

标记

  • 46
  • 8
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SMN1 antibody is un-conjugated

应用范围

  • 72
  • 32
  • 27
  • 22
  • 20
  • 13
  • 13
  • 12
  • 10
  • 9
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF)

克隆位点

3D2
  • 原理

    SMN1 antibody

    纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    survival of motor neuron 2, centromeric

    亚型

    IgG1
  • 应用备注

    WB: 1:1000-1:6000, IF: 1:50-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    SMN1 (Survival of Motor Neuron 1, Telomeric (SMN1))

    别名

    SMN1

    背景

    Synonyms: Survival motor neuron protein|Component of gems 1|Gemin-1|SMN1|SMN|SMNT

    Background: The survival of motor neurons(SMN) genes are the disease genes of spinal muscular atrophy(SMA), a common motor neuron degenerative disease. The level of SMN protein correlates with phenotypic severity of SMA. SMA patients lack a functional SMN1 gene, but they possess an intact SMN2 gene, which though nearly identical to SMN1, is only partially functional, because a large majority of SMN2 transcripts lack exon 7, resulting in production of a truncated, less stable SMN protein. This antibody can recognize human,mouse and rat SMN.

    分子量

    38 kDa

    UniProt

    Q16637

    途径

    Ribonucleoprotein Complex Subunit Organization
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