SMN1 抗体
Quick Overview for SMN1 抗体 (ABIN7119175)
抗原
See all SMN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- SMN1 antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- survival of motor neuron 2, centromeric
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亚型
- IgG1
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应用备注
- WB: 1:1000-1:6000, IF: 1:50-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SMN1 (Survival of Motor Neuron 1, Telomeric (SMN1))
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别名
- SMN1
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背景
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Synonyms: Survival motor neuron protein|Component of gems 1|Gemin-1|SMN1|SMN|SMNT
Background: The survival of motor neurons(SMN) genes are the disease genes of spinal muscular atrophy(SMA), a common motor neuron degenerative disease. The level of SMN protein correlates with phenotypic severity of SMA. SMA patients lack a functional SMN1 gene, but they possess an intact SMN2 gene, which though nearly identical to SMN1, is only partially functional, because a large majority of SMN2 transcripts lack exon 7, resulting in production of a truncated, less stable SMN protein. This antibody can recognize human,mouse and rat SMN.
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分子量
- 38 kDa
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UniProt
- Q16637
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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