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SH3BP4 抗体 (AA 615-963)

This 兔 多克隆 anti-SH3BP4 antibody specifically detects SH3BP4 in WB, ELISA, IP 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7119024
发货至: 中国
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Quick Overview for SH3BP4 抗体 (AA 615-963) (ABIN7119024)

抗原

See all SH3BP4 抗体
SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))

适用

  • 20
  • 6
  • 6
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 16
  • 4
  • 1

克隆类型

  • 18
  • 3
多克隆

标记

  • 16
  • 1
  • 1
  • 1
  • 1
  • 1
This SH3BP4 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)
  • 抗原表位

    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 615-963

    原理

    SH3BP4 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 615-963aa

    Immunogen: SH3-domain binding protein 4

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))

    别名

    SH3BP4

    背景

    Synonyms: SH3 domain-binding protein 4|EH-binding protein 10|Transferrin receptor-trafficking protein|SH3BP4|BOG25|EHB10|TTP

    Background: May function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis. Alternatively, may act as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy.

    分子量

    120 kDa

    基因ID

    23677

    UniProt

    Q9P0V3
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