SH3BP4 抗体 (AA 615-963)
Quick Overview for SH3BP4 抗体 (AA 615-963) (ABIN7119024)
抗原
See all SH3BP4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 615-963
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原理
- SH3BP4 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 615-963aa
Immunogen: SH3-domain binding protein 4
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))
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别名
- SH3BP4
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背景
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Synonyms: SH3 domain-binding protein 4|EH-binding protein 10|Transferrin receptor-trafficking protein|SH3BP4|BOG25|EHB10|TTP
Background: May function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis. Alternatively, may act as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy.
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分子量
- 120 kDa
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基因ID
- 23677
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UniProt
- Q9P0V3
抗原
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