SH3BP4 抗体
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北京 101111
Quick Overview for SH3BP4 抗体 (ABIN306590)
抗原
See all SH3BP4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Sheep anti Human Guanalyate Kinase GKWW domain (MAGI)
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交叉反应
- 人
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产品特性
- Membrane-associated guanylate kinase with inverted orientation (MAGI3) is a novel, 130 kDa guanylate kinase which is part of a family of multi-PDZ domain containing guanylate kinases. These guanylate kinases are localized to epithelial cell tight junctions. MAGI3 and PTEN/MMAC cooperate to modulate the kinase activity of AKT/protein kinase B (PKB). MAGI3 positions the PTEN/MMAC phosphatase to specific subcellular locations that are involved with the regulation of cell proliferation and survival. MAGI3, as well as other proteins in this family, are made up of an N-terminal guanylate kinase domain, followed by a WW domain, named for two conserved tryptophan residues and first identified as two repeats in mouse YAP65, which is then followed by 6 PDZ domains.
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纯化方法
- Ammonium Sulfate Precipitation
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免疫原
- Recombinant protein corresponding to the guanylate kinase-WW domain of MAGI-3.
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亚型
- IgG
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anti-SH3-Domain Binding Protein 4 (SH3BP4) (AA 402-429) antibody
SH3BP4 适用: 人 WB 宿主: 兔 Polyclonal RB39861 unconjugated
anti-SH3-Domain Binding Protein 4 (SH3BP4) (AA 1-110) antibodySH3BP4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B6 unconjugated
anti-SH3-Domain Binding Protein 4 (SH3BP4) (AA 1-110) antibodySH3BP4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SH3-Domain Binding Protein 4 (SH3BP4) (AA 1-110) antibodySH3BP4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-SH3-Domain Binding Protein 4 (SH3BP4) (N-Term) antibodySH3BP4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain Binding Protein 4 (SH3BP4) (AA 71-120) antibodySH3BP4 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 斑马鱼, 兔, Bat, Hamster, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain Binding Protein 4 (SH3BP4) (C-Term) antibodySH3BP4 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Antibody detects MAGI-3 by Western blot at 1-10 μg/mL. Detects a 130 kDa band in cells transfected with full-length MAGI-3 protein. Optimal concentration should be evaluated by serial dilutions.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))
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别名
- Membrane AssociatedGuanalyate Kinase GKWW domain (MAGI)
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背景
- Sheep anti-Membrane-associated guanylate cyclase of inverted orientation-3, Guanylate Kinase-WW domains
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UniProt
- Q9H2V6
抗原
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