SETDB1 抗体
Quick Overview for SETDB1 抗体 (ABIN7118993)
抗原
See all SETDB1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SETDB1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- SET domain, bifurcated 1
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SETDB1 (SET Domain, Bifurcated 1 (SETDB1))
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别名
- SETDB1
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背景
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Synonyms: Histone-lysine N-methyltransferase SETDB1|ERG-associated protein with SET domain (ESET)|Histone H3-K9 methyltransferase 4 (H3-K9-HMTase 4)|Lysine N-methyltransferase 1E|SET domain bifurcated 1|SETDB1|ESET|KIAA0067|KMT1E
Background: This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.
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分子量
- 210 kDa
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基因ID
- 9869
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UniProt
- Q15047
抗原
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