STRAP 抗体
Quick Overview for STRAP 抗体 (ABIN7118930)
抗原
See all STRAP 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- STRAP antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- serine/threonine kinase receptor associated protein
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亚型
- IgG
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anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 1-350) antibody
STRAP 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (N-Term) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 242-269), (C-Term) antibodySTRAP 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20860 unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (N-Term) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 101-150) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (C-Term) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) antibodySTRAP 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 281-330) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 1-350) antibodySTRAP 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 78-104), (N-Term) antibodySTRAP 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- STRAP (Serine/threonine Kinase Receptor Associated Protein (STRAP))
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别名
- STRAP
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背景
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Synonyms: Serine-threonine kinase receptor-associated protein|MAP activator with WD repeats|UNR-interacting protein|WD-40 repeat protein PT-WD|STRAP|MAWD|UNRIP
Background: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. STRAP plays a role in the cellular distribution of the SMN complex. Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein.
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分子量
- 39 kDa
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基因ID
- 11171
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UniProt
- Q9Y3F4
抗原
-
