STK36 抗体
Quick Overview for STK36 抗体 (ABIN7118925)
抗原
See all STK36 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- serine/threonine kinase 36, fused homolog(Drosophila)
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亚型
- IgG
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anti-serine/threonine Kinase 36 (STK36) (AA 1-1315) antibody
STK36 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 36 (STK36) (Internal Region) antibodySTK36 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 36 (STK36) (AA 1-1315) antibodySTK36 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-serine/threonine Kinase 36 (STK36) (AA 250-450) antibodySTK36 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 36 (STK36) (AA 387-436) antibodySTK36 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- STK36 (serine/threonine Kinase 36 (STK36))
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别名
- STK36
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背景
- Synonyms:KIAA1278 Background:Serine/threonine protein kinase which plays an important role in the sonic hedgehog(Shh) pathway by regulating the activity of GLI transcription factors(PubMed:10806483). Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization(PubMed:10806483). GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur(PubMed:10806483). Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function(By similarity). Essential for construction of the central pair apparatus of motile cilia.
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分子量
- 144 kDa
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基因ID
- 27148
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UniProt
- Q9NRP7
抗原
-
