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STK36 抗体 (Internal Region)

STK36 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259306
发货至: 中国
  • 抗原 See all STK36 抗体
    STK36 (serine/threonine Kinase 36 (STK36))
    抗原表位
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    人, 小鼠, 大鼠
    宿主
    • 17
    • 2
    • 1
    克隆类型
    • 20
    多克隆
    标记
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This STK36 antibody is un-conjugated
    应用范围
    • 12
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    STK36 Antibody detects endogenous levels of total STK36.
    预测反应
    Pig,Bovine,Horse,Sheep,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human STK36, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product STK36 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    STK36 (serine/threonine Kinase 36 (STK36))
    别名
    STK36 (STK36 产品)
    别名
    FU antibody, fused-like antibody, 1700112N14Rik antibody, B930045J24 antibody, Fused antibody, mKIAA1278 antibody, fu antibody, si:dkey-180i4.3 antibody, zgc:152944 antibody, serine/threonine kinase 36 antibody, serine/threonine kinase 36 (fused homolog, Drosophila) antibody, STK36 antibody, Stk36 antibody, stk36 antibody
    背景

    Description: Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors (PubMed:10806483). Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization (PubMed:10806483). GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur (PubMed:10806483). Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function (By similarity). Essential for construction of the central pair apparatus of motile cilia.

    Gene: STK36

    分子量
    170 kDa
    基因ID
    27148
    UniProt
    Q9NRP7
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