SUN1 抗体
Quick Overview for SUN1 抗体 (ABIN7118769)
抗原
See all SUN1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SUN1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- unc-84 homolog A(C. elegans)
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.1 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SUN1 (Sad1 and UNC84 Domain Containing 1 (SUN1))
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别名
- SUN1
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背景
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Synonyms: SUN domain-containing protein 1|Protein unc-84 homolog A|Sad1/unc-84 protein-like 1|SUN1|KIAA0810|UNC84A
Background: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration(INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes(NPCs)(By similarity). Required for efficient localization of SYNE4 in the nuclear envelope(By similarity).
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分子量
- 90 kDa
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基因ID
- 6821
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UniProt
- O94901
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途径
- Maintenance of Protein Location
抗原
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