SUN1 抗体
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- 抗原 See all SUN1 抗体
- SUN1 (Sad1 and UNC84 Domain Containing 1 (SUN1))
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This SUN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein corresponding to C-terminal human SUN1.
- 克隆位点
- 2C4
- 亚型
- IgG
- Top Product
- Discover our top product SUN1 Primary Antibody
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anti-Sad1 and UNC84 Domain Containing 1 (SUN1) (N-Term) antibody
SUN1 适用: 人, 大鼠, 小鼠, 兔, Cow, 犬, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 1 (SUN1) (AA 1-257) antibodySUN1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 1 (SUN1) antibodySUN1 适用: 人 WB, IF, IP, ICC 宿主: 兔 Monoclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 1 (SUN1) (AA 2-105) antibodySUN1 适用: Arabidopsis thaliana WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 1 (SUN1) (AA 1-257) antibodySUN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D10 unconjugated
anti-Sad1 and UNC84 Domain Containing 1 (SUN1) (AA 22-173) antibodySUN1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- SUN1 (Sad1 and UNC84 Domain Containing 1 (SUN1))
- 别名
- SUN1 (SUN1 产品)
- 别名
- UNC84A antibody, 4632417G13Rik antibody, 5730434D03Rik antibody, Unc84a antibody, mKIAA0810 antibody, Sun domain-containing protein 1 antibody, Sad1 and UNC84 domain containing 1 antibody, sun-1 antibody, SUN1 antibody, Sun1 antibody
- 背景
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Synonyms: SUN domain-containing protein 1, Protein unc-84 homolog A, Sad1/unc-84 protein-like 1, SUN1, KIAA0810, UNC84A
Background: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Involved in telomere attachment to nuclear envelope in the prophase of meiosis implicating a SUN1/2:KASH5 LINC complex in which SUN1 and SUN2 seem to act at least partial redundantly. Required for gametogenesis and involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Helps to define the distribution of nuclear pore complexes (NPCs). Required for efficient localization of SYNE4 in the nuclear envelope. May be involved in nuclear remodeling during sperm head formation in spermatogenenis. May play a role in DNA repair by suppressing non-homologous end joining repair to facilitate the repair of DNA cross-links.
- 基因ID
- 23353
- UniProt
- O94901
- 途径
- Maintenance of Protein Location
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