RICTOR 抗体
Quick Overview for RICTOR 抗体 (ABIN7118724)
抗原
See all RICTOR 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RICTOR antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1-60AA
Immunogen: rapamycin-insensitive companion of mTOR
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亚型
- IgG
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anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1-98) antibody
RICTOR 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) antibodyRICTOR 适用: 人, 小鼠, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 7B3 unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (C-Term) antibodyRICTOR 适用: 人 WB, IHC, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1-245) antibodyRICTOR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) antibodyRICTOR 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1-99) antibodyRICTOR 适用: 人 WB, ELISA, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1-265) antibodyRICTOR 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 252-281), (N-Term) antibodyRICTOR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB11675 unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 236-267) antibodyRICTOR 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1617-1650) antibodyRICTOR 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000-1:5000, IHC: 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- RICTOR (RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))
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别名
- RICTOR
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背景
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Synonyms: Rapamycin-insensitive companion of mTOR|AVO3 homolog (hAVO3)|RICTOR|KIAA1999
Background: Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'. Plays an essential role in embryonic growth and development.
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分子量
- 192 kDa
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基因ID
- 253260
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UniProt
- Q6R327
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events
抗原
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