RRP8 抗体
Our Local Distributor
北京 101111
Quick Overview for RRP8 抗体 (ABIN7118623)
抗原
See all RRP8 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- RRP8 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- ribosomal RNA processing 8, methyltransferase, homolog(yeast)
-
亚型
- IgG
-
-
anti-Ribosomal RNA Processing 8 (RRP8) antibody
RRP8 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (Internal Region) antibodyRRP8 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (AA 1-456) antibodyRRP8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (AA 89-138) antibodyRRP8 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (AA 271-320) antibodyRRP8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (AA 100-149) antibodyRRP8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ribosomal RNA Processing 8 (RRP8) (N-Term) antibodyRRP8 适用: 人, 大鼠, Cow, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- RRP8 (Ribosomal RNA Processing 8 (RRP8))
-
别名
- RRP8
-
背景
-
Synonyms: Ribosomal RNA-processing protein 8|Cerebral protein 1|Nucleomethylin|RRP8|KIAA0409|NML
Background: Essential component of the eNoSC(energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9'(H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.
-
分子量
- 51 kDa
-
基因ID
- 23378
-
UniProt
- O43159
抗原
-
