ARHGEF7 抗体
Quick Overview for ARHGEF7 抗体 (ABIN7118495)
抗原
See all ARHGEF7 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ARHGEF7 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- Rho guanine nucleotide exchange factor(GEF) 7
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亚型
- IgG
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应用备注
- WB: 1:1000-1:4000, IP: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))
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别名
- ARHGEF7
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背景
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Synonyms: Rho guanine nucleotide exchange factor 7|Beta-Pix|COOL-1|PAK-interacting exchange factor beta|p85|ARHGEF7|COOL1|KIAA0142|P85SPR|PAK3BP|PIXB
Background: Acts as a RAC1 guanine nucleotide exchange factor(GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions(By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
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分子量
- 70 kDa
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基因ID
- 8874
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UniProt
- Q14155
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation
抗原
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