ARHGEF5 抗体
Quick Overview for ARHGEF5 抗体 (ABIN7118494)
抗原
See all ARHGEF5 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ARHGEF5 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- Rho guanine nucleotide exchange factor(GEF) 5
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))
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别名
- ARHGEF5
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背景
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Synonyms: Rho guanine nucleotide exchange factor 5|Ephexin-3|Guanine nucleotide regulatory protein TIM|Oncogene TIM|Transforming immortalized mammary oncogene|p60 TIM|ARHGEF5|TIM
Background: Guanine nucleotide exchange factor which activates Rho GTPases(PubMed:15601624). Strongly activates RHOA(PubMed:15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1(By similarity). Involved in regulation of cell shape and actin cytoskeletal organization(PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia(PubMed:14662653). Required for SRC-induced podosome formation(By similarity). Involved in positive regulation of immature dendritic cell migration(By similarity).
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分子量
- 60 kDa
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基因ID
- 7984
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UniProt
- Q12774
抗原
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