ARHGEF5 抗体 (Internal Region)
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北京 101111
Quick Overview for ARHGEF5 抗体 (Internal Region) (ABIN6257676)
抗原
See all ARHGEF5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- ARHGEF5 Antibody detects endogenous levels of total ARHGEF5.
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预测反应
- Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human ARHGEF5, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5) antibody
ARHGEF5 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5) (AA 1-519) antibodyARHGEF5 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4D10-D11 unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5) antibodyARHGEF5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5) (AA 1-519) antibodyARHGEF5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5) (Internal Region) antibodyVerified ARHGEF5 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5) (AA 1-519) antibodyARHGEF5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5) (N-Term) antibodyARHGEF5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5) (AA 433-507) antibodyARHGEF5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))
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别名
- ARHGEF5
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背景
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Description: Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:15601624). Strongly activates RHOA (PubMed:15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (By similarity). Involved in regulation of cell shape and actin cytoskeletal organization (PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (PubMed:14662653). Required for SRC-induced podosome formation (By similarity). Involved in positive regulation of immature dendritic cell migration (By similarity).
Gene: ARHGEF5
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分子量
- 60 kDa
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基因ID
- 7984
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UniProt
- Q12774
抗原
-
