TRIM27 抗体 (AA 200-513)
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北京 101111
Quick Overview for TRIM27 抗体 (AA 200-513) (ABIN7118412)
抗原
See all TRIM27 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 200-513
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原理
- TRIM27 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 200-513aa
Immunogen: tripartite motif-containing 27
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亚型
- IgG
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anti-Tripartite Motif Containing 27 (TRIM27) antibody
TRIM27 适用: 人 WB, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 27 (TRIM27) (AA 214-513) antibodyTRIM27 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 27 (TRIM27) antibodyTRIM27 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 27 (TRIM27) antibodyTRIM27 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 27 (TRIM27) antibodyTRIM27 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 27 (TRIM27) (AA 141-190) antibodyTRIM27 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 27 (TRIM27) (AA 151-200) antibodyTRIM27 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 27 (TRIM27) (Middle Region) antibodyTRIM27 适用: 人, 小鼠, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TRIM27 (Tripartite Motif Containing 27 (TRIM27))
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别名
- TRIM27
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背景
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Synonyms: Zinc finger protein RFP|RING finger protein 76|Ret finger protein|Tripartite motif-containing protein 27|TRIM27|RFP|RNF76
Background: E3 ubiquitin-protein ligase that mediates ubiquitination of PIK3C2B and inhibits its activity, mediates the formation of 'Lys-48'-linked polyubiquitin chains, the function inhibits CD4 T-cell activation. Acts as a regulator of retrograde transport: together with MAGEL2, mediates the formation of 'Lys-63'-linked polyubiquitin chains at 'Lys-220' of WASH1, leading to promote endosomal F-actin assembly(PubMed:23452853). Has a transcriptional repressor activity by cooperating with EPC1. Induces apoptosis by activating Jun N-terminal kinase and p38 kinase and also increases caspase-3-like activity independently of mitochondrial events. May function in male germ cell development. Has DNA-binding activity and preferentially bound to double-stranded DNA.
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分子量
- 58 kDa
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基因ID
- 5987
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UniProt
- P14373
抗原
-
