RBPJ 抗体
Quick Overview for RBPJ 抗体 (ABIN7118354)
抗原
See all RBPJ 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- RBPJ antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- recombination signal binding protein for immunoglobulin kappa J region
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亚型
- IgG1
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anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (C-Term) antibody
RBPJ 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 1-29) antibodyRBPJ 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 101-200) antibodyRBPJ 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 243-485) antibodyRBPJ 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 1-487) antibodyRBPJ 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 3-109) antibodyRBPJ 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E12 unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (C-Term) antibodyRBPJ 适用: 人, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 猴, 非洲爪蟾, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 1-260) antibodyRBPJ 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) antibodyRBPJ 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 1-29), (N-Term) antibodyRBPJ 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB36620 unconjugated
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))
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别名
- RBPJ
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背景
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Synonyms: Recombining binding protein suppressor of hairless|CBF-1|J kappa-recombination signal-binding protein|RBP-J kappa (RBP-J, RBP-JK)|Renal carcinoma antigen NY-REN-30|RBPJ|IGKJRB|IGKJRB1|RBPJK|RBPSUH
Background: Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins(Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA. Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions(4 % oxygen)(PubMed:23303788).
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分子量
- 60 kDa
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基因ID
- 3516
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UniProt
- Q06330
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途径
- Notch Signaling, Stem Cell Maintenance, Smooth Muscle Cell Migration
抗原
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