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RASIP1 抗体

The 兔 多克隆 anti-RASIP1 antibody is suitable to detect RASIP1 in samples from 人, 大鼠 和 小鼠. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN7118312
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for RASIP1 抗体 (ABIN7118312)

抗原

See all RASIP1 抗体
RASIP1 (Ras Interacting Protein 1 (RASIP1))

适用

人, 大鼠, 小鼠

宿主

  • 6
  • 2
  • 1

克隆类型

  • 9
多克隆

标记

  • 9
This RASIP1 antibody is un-conjugated

应用范围

  • 8
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    RASIP1 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Ras interacting protein 1

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    RASIP1 (Ras Interacting Protein 1 (RASIP1))

    别名

    RASIP1

    背景

    Synonyms: Ras-interacting protein 1 (Rain)|RASIP1

    Background: Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells(By similarity). May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.

    分子量

    115 kDa

    基因ID

    54922

    UniProt

    Q5U651
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