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RAB8A 抗体

This anti-RAB8A antibody is a 兔 多克隆 antibody detecting RAB8A in WB, ELISA, IF 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7118234
发货至: 中国

Quick Overview for RAB8A 抗体 (ABIN7118234)

抗原

See all RAB8A 抗体
RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

适用

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  • 5
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  • 3
  • 2
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  • 1
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人, 小鼠, 大鼠

宿主

  • 22
  • 11
  • 3

克隆类型

  • 24
  • 13
多克隆

标记

  • 23
  • 2
  • 2
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  • 2
  • 2
This RAB8A antibody is un-conjugated

应用范围

  • 20
  • 8
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  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    RAB8A, member RAS oncogene family

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IP: 1:200-1:2000, IF: 1:10-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

    别名

    RAB8A

    背景

    Synonyms:MEL, Oncogene c mel, RAB8, RAB8A, Ras related protein Rab 8A Background:The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in polarized vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites(AMIS), apical surface formation and lumenogenesis. Together with MYO5B and RAB11A participates in epithelial cell polarization. Plays an important role in ciliogenesis. Together with MICALL2, may also regulate adherens junction assembly. May play a role in insulin-induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore play a role in glucose homeostasis.

    分子量

    24 kDa

    基因ID

    4218

    UniProt

    P61006

    途径

    M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome
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