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RAB10 抗体

This anti-RAB10 antibody is a 兔 多克隆 antibody detecting RAB10 in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7118183
发货至: 中国

Quick Overview for RAB10 抗体 (ABIN7118183)

抗原

See all RAB10 抗体
RAB10 (RAB10, Member RAS Oncogene Family (RAB10))

适用

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  • 2
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人, 小鼠, 大鼠

宿主

  • 32
  • 2
  • 1

克隆类型

  • 32
  • 3
多克隆

标记

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  • 4
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  • 1
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This RAB10 antibody is un-conjugated

应用范围

  • 24
  • 17
  • 9
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    RAB10, member RAS oncogene family

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    RAB10 (RAB10, Member RAS Oncogene Family (RAB10))

    别名

    RAB10

    背景

    Synonyms: Background:The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion(By similarity). That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane. Regulates, for instance, SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane. In parallel, it regulates the transport of TLR4, a toll-like receptor to the plasma membrane and therefore may be important for innate immune response. Plays also a specific role in asymmetric protein transport to the plasma membrane within the polarized neuron and epithelial cells. In neurons, it is involved in axonogenesis through regulation of vesicular membrane trafficking toward the axonal plasma membrane while in epithelial cells, it regulates transport from the Golgi to the basolateral membrane. Moreover, may play a role in the basolateral recycling pathway and in phagosome maturation. According to PubMed:23263280, may play a role in endoplasmic reticulum dynamics and morphology controlling tubulation along microtubules and tubules fusion.

    分子量

    23 kDa

    基因ID

    10890

    UniProt

    P61026

    途径

    Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome
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