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RAB10 抗体 (C-Term)

RAB10 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264550
发货至: 中国
  • 抗原 See all RAB10 抗体
    RAB10 (RAB10, Member RAS Oncogene Family (RAB10))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 39
    • 10
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 36
    • 2
    • 2
    克隆类型
    • 37
    • 3
    多克隆
    标记
    • 17
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RAB10 antibody is un-conjugated
    应用范围
    • 29
    • 22
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Rab10 Antibody detects endogenous levels of total Rab10.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human Rab10, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product RAB10 Primary Antibody
  • 应用备注
    WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    RAB10 (RAB10, Member RAS Oncogene Family (RAB10))
    别名
    RAB10 (RAB10 产品)
    别名
    AW107754 antibody, Ac1075 antibody, zgc:92757 antibody, rab10 antibody, RAB10, member RAS oncogene family antibody, RAB10, member RAS oncogene family L homeolog antibody, RAB10 antibody, Rab10 antibody, rab10 antibody, rab10.L antibody
    背景

    Description: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane. Regulates, for instance, SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane. In parallel, it regulates the transport of TLR4, a toll-like receptor to the plasma membrane and therefore may be important for innate immune response. Plays also a specific role in asymmetric protein transport to the plasma membrane within the polarized neuron and epithelial cells. In neurons, it is involved in axonogenesis through regulation of vesicular membrane trafficking toward the axonal plasma membrane while in epithelial cells, it regulates transport from the Golgi to the basolateral membrane. Moreover, may play a role in the basolateral recycling pathway and in phagosome maturation. According to PubMed:23263280, may play a role in endoplasmic reticulum dynamics and morphology controlling tubulation along microtubules and tubules fusion.

    Gene: RAB10

    分子量
    23 kDa
    基因ID
    10890
    UniProt
    P61026
    途径
    Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome
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