PP5 抗体
Quick Overview for PP5 抗体 (ABIN7118033)
抗原
See all PP5 (PPP5C) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- protein phosphatase 5, catalytic subunit
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亚型
- IgG
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anti-Protein Phosphatase 5, Catalytic Subunit (PPP5C) antibody
PPP5C 适用: 人 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Protein Phosphatase 5, Catalytic Subunit (PPP5C) antibodyPPP5C 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5A8 unconjugated
anti-Protein Phosphatase 5, Catalytic Subunit (PPP5C) antibodyPPP5C 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 6C2 unconjugated
anti-Protein Phosphatase 5, Catalytic Subunit (PPP5C) antibodyPPP5C 适用: 人, 犬 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 5G5 unconjugated
anti-Protein Phosphatase 5, Catalytic Subunit (PPP5C) (AA 370-488) antibodyPPP5C 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 5, Catalytic Subunit (PPP5C) (AA 1-499) antibodyPPP5C 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 5, Catalytic Subunit (PPP5C) antibodyPPP5C 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 12F7 unconjugated
anti-Protein Phosphatase 5, Catalytic Subunit (PPP5C) antibody (HRP)PPP5C 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 12F7 HRP
anti-Protein Phosphatase 5, Catalytic Subunit (PPP5C) antibody (FITC)PPP5C 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 12F7 FITC
anti-Protein Phosphatase 5, Catalytic Subunit (PPP5C) antibody (Biotin)PPP5C 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 12F7 Biotin
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- PP5 (PPP5C) (Protein Phosphatase 5, Catalytic Subunit (PPP5C))
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别名
- PPP5C
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背景
- Synonyms:PPP5 Background:Serine/threonine-protein phosphatase that dephosphorylates a myriad of proteins involved in different signaling pathways including the kinases CSNK1E, ASK1/MAP3K5, PRKDC and RAF1, the nuclear receptors NR3C1, PPARG, ESR1 and ESR2, SMAD proteins and TAU/MAPT. Implicated in wide ranging cellular processes, including apoptosis, differentiation, DNA damage response, cell survival, regulation of ion channels or circadian rhythms, in response to steroid and thyroid hormones, calcium, fatty acids, TGF-beta as well as oxidative and genotoxic stresses. Participates in the control of DNA damage response mechanisms such as checkpoint activation and DNA damage repair through, for instance, the regulation ATM/ATR-signaling and dephosphorylation of PRKDC and TP53BP1. Inhibits ASK1/MAP3K5-mediated apoptosis induced by oxidative stress. Plays a positive role in adipogenesis, mainly through the dephosphorylation and activation of PPARG transactivation function. Also dephosphorylates and inhibits the anti-adipogenic effect of NR3C1. Regulates the circadian rhythms, through the dephosphorylation and activation of CSNK1E. May modulate TGF-beta signaling pathway by the regulation of SMAD3 phosphorylation and protein expression levels. Dephosphorylates and may play a role in the regulation of TAU/MAPT. Through their dephosphorylation, may play a role in the regulation of ions channels such as KCNH2.
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分子量
- 57 kDa
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基因ID
- 5536
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UniProt
- P53041
抗原
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