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PP5 抗体 (AA 370-488)

PPP5C 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7169288
发货至: 中国
  • 抗原 See all PP5 (PPP5C) 抗体
    PP5 (PPP5C) (Protein Phosphatase 5, Catalytic Subunit (PPP5C))
    抗原表位
    • 8
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 370-488
    适用
    • 60
    • 12
    • 11
    • 7
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    宿主
    • 35
    • 25
    克隆类型
    • 37
    • 23
    多克隆
    标记
    • 34
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PP5 antibody is un-conjugated
    应用范围
    • 50
    • 21
    • 21
    • 17
    • 13
    • 11
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
    交叉反应
    人, 小鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Serine/threonine-protein phosphatase 5 protein (370-488AA)
    亚型
    IgG
    Top Product
    Discover our top product PPP5C Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:2000, IHC:1:200-1:500, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PP5 (PPP5C) (Protein Phosphatase 5, Catalytic Subunit (PPP5C))
    别名
    PPP5C (PPP5C 产品)
    别名
    PP5 antibody, PPP5 antibody, PPT antibody, AU020526 antibody, pp5 antibody, MGC89961 antibody, fc83f08 antibody, im:7146608 antibody, wu:fc83f08 antibody, zgc:110801 antibody, PPP5C antibody, protein phosphatase 5 catalytic subunit antibody, protein phosphatase 5, catalytic subunit antibody, protein phosphatase 5, catalytic subunit S homeolog antibody, serine/threonine-protein phosphatase 5 antibody, PPP5C antibody, Ppp5c antibody, ppp5c.S antibody, ppp5c antibody, LOC592155 antibody, LOC100513542 antibody, LOC100564151 antibody, LOC100186268 antibody, LOC100208775 antibody
    背景

    Background: Serine/threonine-protein phosphatase that dephosphorylates a myriad of proteins involved in different signaling pathways including the kinases CSNK1E, ASK1/MAP3K5, PRKDC and RAF1, the nuclear receptors NR3C1, PPARG, ESR1 and ESR2, SMAD proteins and TAU/MAPT. Implicated in wide ranging cellular processes, including apoptosis, differentiation, DNA damage response, cell survival, regulation of ion channels or circadian rhythms, in response to steroid and thyroid hormones, calcium, fatty acids, TGF-beta as well as oxidative and genotoxic stresses. Participates in the control of DNA damage response mechanisms such as checkpoint activation and DNA damage repair through, for instance, the regulation ATM/ATR-signaling and dephosphorylation of PRKDC and TP53BP1. Inhibits ASK1/MAP3K5-mediated apoptosis induced by oxidative stress. Plays a positive role in adipogenesis, mainly through the dephosphorylation and activation of PPARG transactivation function. Also dephosphorylates and inhibits the anti-adipogenic effect of NR3C1. Regulates the circadian rhythms, through the dephosphorylation and activation of CSNK1E. May modulate TGF-beta signaling pathway by the regulation of SMAD3 phosphorylation and protein expression levels. Dephosphorylates and may play a role in the regulation of TAU/MAPT. Through their dephosphorylation, may play a role in the regulation of ions channels such as KCNH2.

    Aliases: FLJ36922 antibody, FLJ55954 antibody, OTTHUMP00000165834 antibody, PP-T antibody, PP5 antibody, PPP5 antibody, PPP5_HUMAN antibody, Ppp5c antibody, PPT antibody, Protein phosphatase 5, catalytic subunit antibody, Protein phosphatase T antibody, Serine/threonine protein phosphatase 5 antibody, Serine/threonine-protein phosphatase 5 antibody

    UniProt
    P53041
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