PRMT5 抗体 (AA 76-291)
Quick Overview for PRMT5 抗体 (AA 76-291) (ABIN7117928)
抗原
See all PRMT5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 76-291
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原理
- PRMT5 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 76-291aa
Immunogen: protein arginine methyltransferase 5
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))
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别名
- PRMT5
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背景
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Synonyms: Protein arginine N-methyltransferase 5 (PRMT5)|72 kDa ICln-binding protein|Histone-arginine N-methyltransferase PRMT5|Jak-binding protein 1|Shk1 kinase-binding protein 1 homolog (SKB1 homolog, SKB1Hs)|Protein arginine N-methyltransferase 5, N-terminally processed|PRMT5|HRMT1L5|IBP72|JBP1|SKB1
Background: This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 70 kDa
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基因ID
- 10419
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UniProt
- O14744
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途径
- Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development
抗原
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