POLR3D 抗体
Quick Overview for POLR3D 抗体 (ABIN7117681)
抗原
See all POLR3D 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- polymerase(RNA) III(DNA directed) polypeptide D, 44kDa
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亚型
- IgG
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anti-Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D) (AA 1-398) antibody
POLR3D 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D) antibodyPOLR3D 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D) (AA 296-395) antibodyPOLR3D 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4E6 unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D) (Internal Region) antibodyPOLR3D 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- POLR3D (Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D))
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别名
- POLR3D
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背景
- Synonyms:BN51, BN51T Background:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs(EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway(By similarity).
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分子量
- 44 kDa
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基因ID
- 661
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UniProt
- P05423
抗原
-
