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- 抗原 See all POLR3D 抗体
- POLR3D (Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POLR3D antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from internal of Human RPC4.
- 亚型
- IgG
- Top Product
- Discover our top product POLR3D Primary Antibody
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anti-Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D) (AA 1-398) antibody
POLR3D 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D) (Internal Region) antibodyPOLR3D 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D) (AA 296-395) antibodyPOLR3D 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4E6 unconjugated
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- 应用备注
- WB:1:500-1:3000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- POLR3D (Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D))
- 别名
- POLR3D (POLR3D 产品)
- 别名
- 2810426M17Rik antibody, 44kDa antibody, AI326118 antibody, AW489084 antibody, BN51T antibody, RPC4 antibody, TSBN51 antibody, RPC53 antibody, RNA polymerase III subunit D antibody, polymerase (RNA) III (DNA directed) polypeptide D antibody, Polr3d antibody, POLR3D antibody
- 背景
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Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway By similarity.
Ittmann M., Mol. Cell. Biol. 7:3386-3393(1987).
Hu P., Mol. Cell. Biol. 22:8044-8055(2002).
Kalnine N., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.Aliases: POLR3D antibody, BN51 antibody, BN51T antibody, DNA-directed RNA polymerase III subunit RPC4 antibody, RNA polymerase III subunit C4 antibody, DNA-directed RNA polymerase III subunit D antibody, Protein BN51 antibody, RNA polymerase III 47 kDa subunit antibody, RPC53 homolog antibody
- UniProt
- P05423
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