POLK 抗体
Quick Overview for POLK 抗体 (ABIN7117655)
抗原
See all POLK 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- POLK antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- polymerase(DNA directed) kappa
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- POLK (Polymerase (DNA Directed) kappa (POLK))
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别名
- POLK
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背景
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Synonyms: DNA polymerase kappa|DINB protein (DINP)|POLK|DINB1
Background: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3'-5' proofreading exonuclease activity. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity.
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分子量
- 70 kDa
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基因ID
- 51426
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UniProt
- Q9UBT6
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途径
- DNA Damage Repair
抗原
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