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PQBP1 抗体

The 兔 多克隆 anti-PQBP1 antibody is suitable to detect PQBP1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN7117652
发货至: 中国
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中国
北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PQBP1 抗体 (ABIN7117652)

抗原

See all PQBP1 抗体
PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))

适用

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人, 小鼠, 大鼠

宿主

  • 34
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克隆类型

  • 34
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多克隆

标记

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This PQBP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 原理

    PQBP1 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    polyglutamine binding protein 1

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))

    别名

    PQBP1

    背景

    Synonyms: Polyglutamine-binding protein 1 (PQBP-1)|38 kDa nuclear protein containing a WW domain (Npw38)|Polyglutamine tract-binding protein 1|PQBP1|NPW38

    Background: Probably functions as scaffold protein that is part of numerous complexes and thereby plays a role in pre-mRNA splicing, transcription regulation and neuron development. Required for normal alternative splicing of target pre-mRNA species(PubMed:23512658). May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.

    分子量

    38 kDa, 30 kDa

    基因ID

    10084

    UniProt

    O60828

    途径

    Ribonucleoprotein Complex Subunit Organization
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