PGK1 抗体
Quick Overview for PGK1 抗体 (ABIN7117449)
抗原
See all PGK1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PGK1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- phosphoglycerate kinase 1
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PGK1 (Phosphoglycerate Kinase 1 (PGK1))
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别名
- PGK1
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背景
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Synonyms: Phosphoglycerate kinase 1|Cell migration-inducing gene 10 protein|Primer recognition protein 2 (PRP 2)|PGK1|PGKA
Background: The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1, 3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome.
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分子量
- 47 kDa
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基因ID
- 5230
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UniProt
- P00558
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途径
- Cellular Glucan Metabolic Process
抗原
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