PDE12 抗体
Quick Overview for PDE12 抗体 (ABIN7117422)
抗原
See all PDE12 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- phosphodiesterase 12
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亚型
- IgG
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anti-Phosphodiesterase 12 (PDE12) (AA 17-300) antibody
PDE12 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 1-575) antibodyPDE12 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (C-Term) antibodyPDE12 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 犬, 兔, 猴, Pig, Bat, 小鸡, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 290-602) antibodyPDE12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 362-390), (C-Term) antibodyPDE12 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB27765 unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 369-398), (C-Term) antibodyPDE12 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- PDE12 (Phosphodiesterase 12 (PDE12))
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别名
- PDE12
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背景
- Synonyms: Background:Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons(IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system.
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分子量
- 65kd
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基因ID
- 201626
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UniProt
- Q6L8Q7
抗原
-
