PAN2 抗体
Quick Overview for PAN2 抗体 (ABIN7117214)
抗原
See all PAN2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- PAN2 poly(A) specific ribonuclease subunit homolog(S. cerevisiae)
-
亚型
- IgG
-
-
anti-PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2) (AA 628-908) antibody
PAN2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2) (AA 1099-1198) antibodyPAN2 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 6A7 unconjugated
anti-PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2) (AA 700-1000) antibodyPAN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
-
有效期
- 12 months
-
-
- PAN2 (PAN2 Poly(A) Specific Ribonuclease Subunit Homolog (PAN2))
-
别名
- PAN2
-
背景
- Synonyms:KIAA0710, USP52 Background:Catalytic subunit of the poly(A)-nuclease(PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA when the poly(A) stretch is bound by poly(A)-binding protein(PABP), which is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
-
分子量
- 127 kDa
-
基因ID
- 9924
-
UniProt
- Q504Q3
抗原
-
