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Nth Endonuclease III-Like 1 (NTHL1) 抗体

NTHL1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7116939
发货至: 中国
  • 抗原 See all Nth Endonuclease III-Like 1 (NTHL1) 抗体
    Nth Endonuclease III-Like 1 (NTHL1)
    适用
    • 41
    • 12
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 45
    • 1
    克隆类型
    • 44
    • 2
    多克隆
    标记
    • 19
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 30
    • 26
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    nth endonuclease III-like 1(E. coli)
    亚型
    IgG
    Top Product
    Discover our top product NTHL1 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    Nth Endonuclease III-Like 1 (NTHL1)
    别名
    NTHL1 (NTHL1 产品)
    别名
    psmc3 antibody, psmc3-a antibody, nth-like DNA glycosylase 1 S homeolog antibody, nthl1.S antibody
    背景
    Synonyms:NTH1, OCTS3 Background:Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic(AP) lyase function that catalyzes the first step in base excision repair(BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine(8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.
    分子量
    34 kDa
    基因ID
    4913
    UniProt
    P78549
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