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Nth Endonuclease III-Like 1 (NTHL1) 抗体

This 兔 多克隆 antibody specifically detects Nth Endonuclease III-Like 1 in WB 和 ELISA. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7230150
发货至: 中国
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Quick Overview for Nth Endonuclease III-Like 1 (NTHL1) 抗体 (ABIN7230150)

抗原

See all Nth Endonuclease III-Like 1 (NTHL1) 抗体
Nth Endonuclease III-Like 1 (NTHL1)

适用

  • 46
  • 6
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 50
  • 2

克隆类型

  • 34
  • 18
多克隆

标记

  • 28
  • 7
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
非结合性

应用范围

  • 42
  • 25
  • 17
  • 15
  • 14
  • 5
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 原理

    Rabbit Anti-NTHL1 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of NTHL1 protein

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human NTHL1 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Nth Endonuclease III-Like 1 (NTHL1)

    别名

    NTHL1

    背景

    Endonuclease III-like protein 1, hNTH1, Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase, DNA glycosylase/AP lyaseNTHL1 encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity. NTHL1 (Nth Like DNA Glycosylase 1) is a Protein Coding gene. Diseases associated with NTHL1 include Familial Adenomatous Polyposis 3 and Periampullary Adenoma. Among its related pathways are DNA damage_Role of Brca1 and Brca2 in DNA repair and Telomere C-strand (Lagging Strand) Synthesis.

    分子量

    34kD

    基因ID

    4913

    UniProt

    P78549
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