Nth Endonuclease III-Like 1 (NTHL1) 抗体
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Quick Overview for Nth Endonuclease III-Like 1 (NTHL1) 抗体 (ABIN7230150)
抗原
See all Nth Endonuclease III-Like 1 (NTHL1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-NTHL1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of NTHL1 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human NTHL1 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Nth Endonuclease III-Like 1 (NTHL1)
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别名
- NTHL1
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背景
- Endonuclease III-like protein 1, hNTH1, Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase, DNA glycosylase/AP lyaseNTHL1 encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity. NTHL1 (Nth Like DNA Glycosylase 1) is a Protein Coding gene. Diseases associated with NTHL1 include Familial Adenomatous Polyposis 3 and Periampullary Adenoma. Among its related pathways are DNA damage_Role of Brca1 and Brca2 in DNA repair and Telomere C-strand (Lagging Strand) Synthesis.
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分子量
- 34kD
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基因ID
- 4913
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UniProt
- P78549
抗原
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