NMRAL1 抗体
Quick Overview for NMRAL1 抗体 (ABIN7116912)
抗原
See all NMRAL1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- NmrA-like family domain containing 1
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亚型
- IgG
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anti-NmrA-Like Family Domain Containing 1 (NMRAL1) (AA 1-299) antibody
NMRAL1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-NmrA-Like Family Domain Containing 1 (NMRAL1) (AA 1-299) antibodyNMRAL1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-NmrA-Like Family Domain Containing 1 (NMRAL1) (AA 216-265) antibodyNMRAL1 适用: 人, 大鼠, Cow, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-NmrA-Like Family Domain Containing 1 (NMRAL1) (N-Term) antibodyNMRAL1 适用: 大鼠, 小鼠, Cow, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-NmrA-Like Family Domain Containing 1 (NMRAL1) (Middle Region) antibodyNMRAL1 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))
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别名
- NMRAL1
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背景
- Synonyms:HSCARG Background:Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase(ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer.
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分子量
- 33 kDa
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基因ID
- 57407
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UniProt
- Q9HBL8
抗原
-
