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NMRAL1 抗体 (AA 1-299) (FITC)

NMRAL1 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7161663
发货至: 中国
  • 抗原 See all NMRAL1 抗体
    NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))
    抗原表位
    • 7
    • 1
    • 1
    • 1
    AA 1-299
    适用
    • 11
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 10
    • 2
    克隆类型
    • 12
    多克隆
    标记
    • 9
    • 1
    • 1
    • 1
    This NMRAL1 antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human NmrA-like family domain-containing protein 1 protein (1-299AA)
    亚型
    IgG
    Top Product
    Discover our top product NMRAL1 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))
    别名
    NMRAL1 (NMRAL1 产品)
    别名
    HSCARG antibody, SDR48A1 antibody, 1110025F24Rik antibody, AI256624 antibody, RGD1311451 antibody, NmrA like redox sensor 1 antibody, NmrA-like family domain containing 1 antibody, NMRAL1 antibody, Nmral1 antibody
    背景

    Background: Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer.

    Aliases: FLJ25918 antibody, HSCARG antibody, NmrA like family domain containing 1 antibody, NmrA like family domain containing protein 1 antibody, NmrA-like family domain-containing protein 1 antibody, NMRAL1 antibody, NMRL1_HUMAN antibody, SDR48A1 antibody

    UniProt
    Q9HBL8
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