MYO9B 抗体
Quick Overview for MYO9B 抗体 (ABIN7116615)
抗原
See all MYO9B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- MYO9B antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- myosin IXB
-
亚型
- IgG
-
-
anti-Myosin IXB (MYO9B) (N-Term) antibody
MYO9B 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myosin IXB (MYO9B) (N-Term) antibodyMYO9B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myosin IXB (MYO9B) (Internal Region) antibodyVerified MYO9B 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:2000, IP: 1:200-1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- MYO9B (Myosin IXB (MYO9B))
-
别名
- MYO9B
-
背景
-
Synonyms: Unconventional myosin-IXb|Unconventional myosin-9b|MYO9B|MYR5
Background: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions(PubMed:9490638). Also acts as a GTPase activator for RHOA(PubMed:9490638, PubMed:26529257). Plays a role in the regulation of cell migration via its role as RHOA GTPase activator. This is regulated by its interaction with the SLIT2 receptor ROBO1, interaction with ROBO1 impairs interaction with RHOA and subsequent activation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA(PubMed:26529257).
-
分子量
- 230-250 kDa
-
基因ID
- 4650
-
UniProt
- Q13459
抗原
-
