MYO9B 抗体 (AA 304-353)
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北京 101111
Quick Overview for MYO9B 抗体 (AA 304-353) (ABIN1451373)
抗原
See all MYO9B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 304-353
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原理
- Myosin IXb Antibody
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特异性
- Myosin IXb Polyclonal Antibody detects endogenous levels of Myosin IXb protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human MYO9B. AA range:304-353
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MYO9B (Myosin IXB (MYO9B))
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别名
- MYO9B
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背景
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Synonyms: MYO9B, MYR5, Unconventional myosin-IXb, Unconventional myosin-9b
Background: This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin, it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],
Gene Name: MYO9B
Protein Name: Unconventional myosin-IXb
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分子量
- 243 kDa
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基因ID
- 4650
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OMIM
- 602129
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UniProt
- Q13459
抗原
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