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MYO9B 抗体

MYO9B 适用: 人, 小鼠, 大鼠 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7116615
发货至: 中国
  • 抗原 See all MYO9B 抗体
    MYO9B (Myosin IXB (MYO9B))
    适用
    人, 小鼠, 大鼠
    宿主
    • 11
    • 1
    克隆类型
    • 12
    多克隆
    标记
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYO9B antibody is un-conjugated
    应用范围
    • 5
    • 5
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    myosin IXB
    亚型
    IgG
    Top Product
    Discover our top product MYO9B Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IP: 1:200-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    MYO9B (Myosin IXB (MYO9B))
    别名
    MYO9B (MYO9B 产品)
    别名
    CELIAC4 antibody, MYR5 antibody, MYO9B antibody, fb53f01 antibody, wu:fb53f01 antibody, wu:fc47c07 antibody, si:dkeyp-66d1.8 antibody, myosin IXB antibody, myosin IXb antibody, unconventional myosin-IXb antibody, MYO9B antibody, Myo9b antibody, myo9b antibody, LOC100450445 antibody
    背景
    Synonyms:MYR5 Background:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions(PubMed:9490638). Also acts as a GTPase activator for RHOA(PubMed:9490638, PubMed:26529257). Plays a role in the regulation of cell migration via its role as RHOA GTPase activator. This is regulated by its interaction with the SLIT2 receptor ROBO1, interaction with ROBO1 impairs interaction with RHOA and subsequent activation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA(PubMed:26529257).
    分子量
    230-250kd
    基因ID
    4650
    UniProt
    Q13459
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