MLF1 抗体
Quick Overview for MLF1 抗体 (ABIN7116569)
抗原
See all MLF1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MLF1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- myeloid leukemia factor 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- MLF1 (Myeloid Leukemia Factor 1 (MLF1))
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别名
- MLF1
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背景
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Synonyms: Myeloid leukemia factor 1|Myelodysplasia-myeloid leukemia factor 1|MLF1
Background: Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
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分子量
- 31 kDa
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基因ID
- 4291
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UniProt
- P58340
抗原
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